Journal article
Association of breast cancer risk loci with breast cancer survival
M Barrdahl, F Canzian, S Lindström, I Shui, A Black, RN Hoover, RG Ziegler, JE Buring, SJ Chanock, WR Diver, SM Gapstur, MM Gaudet, GG Giles, C Haiman, BE Henderson, S Hankinson, DJ Hunter, AD Joshi, P Kraft, IM Lee Show all
International Journal of Cancer | Published : 2015
DOI: 10.1002/ijc.29446
Abstract
The survival of breast cancer patients is largely influenced by tumor characteristics, such as TNM stage, tumor grade and hormone receptor status. However, there is growing evidence that inherited genetic variation might affect the disease prognosis and response to treatment. Several lines of evidence suggest that alleles influencing breast cancer risk might also be associated with breast cancer survival. We examined the associations between 35 breast cancer susceptibility loci and the disease over-all survival (OS) in 10,255 breast cancer patients from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3) of which 1,379 died, including 754 of breast cancer. We al..
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Awarded by National Institutes of Health
Funding Acknowledgements
Grant sponsor: US National Institutes of Health; Grant sponsor: National Cancer Institute; Grant numbers: U01-CA98233-07, U01-CA98710-06, U01-CA98216-06 and U01-CA98758-07; Grant sponsor: Intramural Research Program of National Institutes of Health and National Cancer Institute, Division of Cancer Epidemiology and Genetics; Grant sponsor: Hellenic Health Foundation; Grant sponsor: Stavros Niarchos Foundation; Grant sponsor: Department of Defense Prostate Cancer Research Program Fellowship